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Smoking dependency

EFO Endpoint Browser PheWeb

SMOKING_DEPEND

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F17
  • Hospital discharge: ICD-9 — 3051
  • Cause of death: ICD-10 — F17
  • Cause of death: ICD-9 — 3051

2 out of 7 registries used, show all original rules.

2532

4. Check minimum number of events

None

2532

5. Include endpoints

None

2532

6. Filter based on genotype QC (FinnGen only)

2443

Control definitions (FinnGen only)

Control exclude SMOKING

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 F10-F19
Name in latin Perturbationes mentis et modi se gerendi ex usu tabaci

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 20684 9243 11340
Only index persons 19695 8992 10703
Unadjusted period prevalence (%)
Whole population 0.29 0.26 0.32
Only index persons 0.37 0.33 0.41
Median age at first event (years)
Whole population 56.15 53.81 58.11
Only index persons 55.85 53.56 57.78

-FinnGen-

Key figures

All Female Male
Number of individuals 2443 1270 1173
Unadjusted period prevalence (%) 0.60 0.55 0.65
Median age at first event (years) 55.85 52.76 59.21

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: SMOKING_DEPEND – Smoking dependency

GWS hits: 2

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