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Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances

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F5_OTHERSUB

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F19
  • Hospital discharge: ICD-9 — 3059|3049
  • Hospital discharge: ICD-8 — 304[8-9]
  • Cause of death: ICD-10 — F19
  • Cause of death: ICD-9 — 3059|3049
  • Cause of death: ICD-8 — 304[8-9]

2 out of 7 registries used, show all original rules.

2643

4. Check minimum number of events

None

2643

5. Include endpoints

None

2643

6. Filter based on genotype QC (FinnGen only)

2491

Control definitions (FinnGen only)

Control exclude F5_SUBSNOALCO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F10-F19
Name in latin Perturbationes mentis et modi se gerendi ex usu medicamentorum multorum et aliarum substantiarum psychotropicarum

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 40059 12579 27166
Only index persons 33514 10977 22537
Unadjusted period prevalence (%)
Whole population 0.63 0.36 0.76
Only index persons 0.71 0.40 0.86
Median age at first event (years)
Whole population 27.93 27.54 28.02
Only index persons 26.73 26.08 27.05

-FinnGen-

Key figures

All Female Male
Number of individuals 2491 989 1502
Unadjusted period prevalence (%) 0.67 0.43 0.83
Median age at first event (years) 28.11 28.08 28.13

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: F5_OTHERSUB – Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances

GWS hits: 2

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