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Mental and behavioural disorders due to opioids

DOID EFO Endpoint Browser PheWeb

F5_OPIOIDS

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F11
  • Hospital discharge: ICD-9 — 3040|3055
  • Hospital discharge: ICD-8 — 304[0-1]
  • Cause of death: ICD-10 — F11
  • Cause of death: ICD-9 — 3040|3055
  • Cause of death: ICD-8 — 304[0-1]

2 out of 7 registries used, show all original rules.

1272

4. Check minimum number of events

None

1272

5. Include endpoints

None

1272

6. Filter based on genotype QC (FinnGen only)

1197

Control definitions (FinnGen only)

Control exclude F5_SUBSNOALCO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F10-F19
Name in latin Perturbationes mentis et modi se gerendi ex usu opioidum

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 18149 6045 11977
Only index persons 16497 5574 10923
Unadjusted period prevalence (%)
Whole population 0.28 0.17 0.33
Only index persons 0.35 0.20 0.42
Median age at first event (years)
Whole population 29.82 29.12 30.11
Only index persons 29.40 28.45 29.89

-FinnGen-

Key figures

All Female Male
Number of individuals 1197 532 665
Unadjusted period prevalence (%) 0.31 0.23 0.37
Median age at first event (years) 31.27 30.61 31.80

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: F5_OPIOIDS – Mental and behavioural disorders due to opioids

GWS hits: -

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