No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
Control exclude
G6_AD_WIDE, F5_DEMENTIA, F5_DEMENTIA_U, F5_PSYCH, NEURODIS, MEMLOSS, TRAUMBRAIN_NONCONCUS
Extra metadata
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Alzheimer’s disease (Early onset) (more control exclusions)
based on the number of shared cases.
Broader endpoints:
- Alzheimer’s disease (Early onset)
- Alzheimer’s disease, wide definition
- Alzheimer’s disease, wide definition (more control exclusions)
- Any dementia
- Any dementia (more control exclusions)
Narrower endpoints:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 33683 | 20929 | 12434 |
| Only index persons | 27051 | 17263 | 9788 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.50 | 0.60 | 0.35 |
| Only index persons | 0.54 | 0.63 | 0.37 |
| Median age at first event (years) | |||
| Whole population | 80.07 | 81.15 | 78.31 |
| Only index persons | 80.19 | 81.30 | 78.22 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1451 | 662 | 789 |
| Unadjusted period prevalence (%) | 0.37 | 0.29 | 0.43 |
| Median age at first event (years) | 76.16 | 73.89 | 78.06 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: AD_EO_EXMORE – Alzheimer’s disease (Early onset) (more control exclusions)
GWS hits: 1
Loading Relationships table