Any dementia (more control exclusions)

KRA_PSY_DEMENTIA_EXMORE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F00-F09, F05.1, G30
  • Hospital discharge: ICD-9 290|2912A|2828C|2941A|3310A|3311A|4378A
  • Hospital discharge: ICD-8 290
  • Cause of death: ICD-10 F00-F09, F05.1, G30
  • Cause of death: ICD-9 290|2912A|2828C|2941A|3310A|3311A|4378A
  • Cause of death: ICD-8 290

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude KRA_PSY_ANYMENTAL

Extra metadata

First used in FinnGen datafreeze DF9

Case counts by codes

FinnGen case counts by registry codes:

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Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 385404 236885 144096
Only index persons 275980 173824 102156
Unadjusted period prevalence (%)
Whole population 5.73 6.79 4.03
Only index persons 5.47 6.39 3.90
Median age at first event (years)
Whole population 81.77 82.80 80.17
Only index persons 82.36 83.39 80.60

-FinnGen-

Key figures

All Female Male
Number of individuals 16209 6836 9373
Unadjusted period prevalence (%) 4.23 2.97 5.16
Median age at first event (years) 79.46 79.69 79.29

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: KRA_PSY_DEMENTIA_EXMORE – Any dementia (more control exclusions)

GWS hits: 11

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