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Alzheimer’s disease (Atypical or mixed)

AD_AM

Alzheimer's disease: A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

2481

4. Check minimum number of events

None

2481

5. Include endpoints

None

2481

6. Filter based on genotype QC (FinnGen only)

2419

Control definitions (FinnGen only)

Control exclude G6_ALZHEIMER

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 2419 968 1451
Unadjusted period prevalence (%) 0.65 0.42 0.80
Median age at first event (years) 81.32 81.64 81.10

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: AD_AM – Alzheimer’s disease (Atypical or mixed)

GWS hits: -

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