Vascular dementia (multiple infarctions)

VD_MI

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F01.1
  • Hospital discharge: ICD-9 4378
  • Cause of death: ICD-10 F01.1
  • Cause of death: ICD-9 4378

2 out of 7 registries used, show all original rules.

538

4. Check minimum number of events

None

538

5. Include endpoints

None

538

6. Filter based on genotype QC (FinnGen only)

525

Control definitions (FinnGen only)

Control exclude F5_DEMENTIA, G6_ALZHEIMER, G6_AD_WIDE

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 F01
Name in latin Dementia e multis infarctibus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17740 8997 8189
Only index persons 5236 2717 2519
Unadjusted period prevalence (%)
Whole population 0.25 0.26 0.23
Only index persons 0.10 0.10 0.10
Median age at first event (years)
Whole population 79.25 80.73 77.74
Only index persons 80.26 82.38 77.98

-FinnGen-

Key figures

All Female Male
Number of individuals 525 137 388
Unadjusted period prevalence (%) 0.17 0.06 0.21
Median age at first event (years) 76.29 78.09 75.66

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: VD_MI – Vascular dementia (multiple infarctions)

GWS hits: 1

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