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Dementia due to Parkinson's disease (more control exclusions)

Endpoint Browser PheWeb

PD_DEMENTIA_EXMORE

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

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2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

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4. Check minimum number of events

None

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5. Include endpoints

None

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6. Filter based on genotype QC (FinnGen only)

None

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Control definitions (FinnGen only)

Control exclude G6_PARKINSON, F5_PSYCH, NEURODIS

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9967 4278 5570
Only index persons 8196 3544 4652
Unadjusted period prevalence (%)
Whole population 0.14 0.12 0.16
Only index persons 0.16 0.13 0.18
Median age at first event (years)
Whole population 77.63 78.85 76.70
Only index persons 77.59 78.87 76.63

-FinnGen-

Key figures

All Female Male
Number of individuals 589 194 395
Unadjusted period prevalence (%) 0.17 0.08 0.22
Median age at first event (years) 76.75 77.53 76.36

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: PD_DEMENTIA_EXMORE – Dementia due to Parkinson's disease (more control exclusions)

GWS hits: 1

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