Dementia in other diseases classified elsewhere

F5_DEMINOTH

obsolete_dementia: ['An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.']

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F02*
  • Cause of death: ICD-10 F02*

2 out of 7 registries used, show all original rules.

1308

4. Check minimum number of events

None

1308

5. Include endpoints

None

1308

6. Filter based on genotype QC (FinnGen only)

1268

Control definitions (FinnGen only)

Control exclude F5_ORGANIC

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 19287 9396 9701
Only index persons 16089 8004 8085
Unadjusted period prevalence (%)
Whole population 0.27 0.27 0.27
Only index persons 0.30 0.29 0.31
Median age at first event (years)
Whole population 75.14 75.93 74.35
Only index persons 74.85 75.59 74.11

-FinnGen-

Key figures

All Female Male
Number of individuals 1268 567 701
Unadjusted period prevalence (%) 0.32 0.25 0.39
Median age at first event (years) 71.64 68.69 74.03

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: F5_DEMINOTH – Dementia in other diseases classified elsewhere

GWS hits: 1

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