inflammatory bowel disease: A spectrum of small and large bowel inflammatory diseases of unknown etiology. It includes Crohn's disease, ulcerative colitis, and colitis of indeterminate type.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditions
|
9363 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
9363 |
6. Filter based on genotype QC (FinnGen only) |
9083 |
Control definitions (FinnGen only)
Control exclude
K11_IBD_STRICT_PSC
Control conditions
not K11_KELAIBD
Extra metadata
Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF9
Similar endpoints
↥List of similar endpoints to
Inflammatory bowel disease, strict (require KELA)
based on the number of shared cases.
Broader endpoints:
- IBD patients in KELA-register
- Inflammatory bowel disease
- Noninfective enteritis and colitis
- Autoimmune diseases related-to ILD
- Autoimmune diseases
Narrower endpoints:
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 64105 | 29608 | 34206 |
| Only index persons | 60335 | 28315 | 32020 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.90 | 0.85 | 0.96 |
| Only index persons | 1.14 | 1.04 | 1.22 |
| Median age at first event (years) | |||
| Whole population | 36.15 | 35.44 | 36.65 |
| Only index persons | 35.35 | 34.89 | 35.77 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 9083 | 4742 | 4341 |
| Unadjusted period prevalence (%) | 2.22 | 2.06 | 2.39 |
| Median age at first event (years) | 37.19 | 34.67 | 39.95 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: K11_IBD_STRICT – Inflammatory bowel disease, strict (require KELA)
GWS hits: 67
Loading Relationships table