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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Crohn disease

DOID EFO Endpoint Browser

K11_CROHN

Crohn's disease: A gastrointestinal disorder characterized by chronic inflammation involving all layers of the intestinal wall, noncaseating granulomas affecting the intestinal wall and regional lymph nodes, and transmural fibrosis. Crohn disease most commonly involves the terminal ileum; the colon is the second most common site of involvement.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K50
  • Hospital discharge: ICD-9 — 555
  • Hospital discharge: ICD-8 — 5630
  • Cause of death: ICD-10 — K50
  • Cause of death: ICD-9 — 555
  • Cause of death: ICD-8 — 5630

2 out of 7 registries used, show all original rules.

4760

4. Check minimum number of events

None

4760

5. Include endpoints

None

4760

6. Filter based on genotype QC (FinnGen only)

4601

Control definitions (FinnGen only)

Control exclude K11_ENERCOLNONINF

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K50-K52
Name in latin Morbus Crohn

Similar endpoints

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Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 4601 2548 2053
Unadjusted period prevalence (%) 1.12 1.11 1.13
Median age at first event (years) 41.71 39.36 44.62

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: K11_CROHN – Crohn disease

GWS hits: -

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