Other Crohn's disease

CHRONOTH

ileocolitis: Ileocolitis or ileal Crohn's is the most common type of Crohn's disease. It affects both the ileum (small intestine) and the colon.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K50.8
  • Cause of death: ICD-10 K50.8

2 out of 7 registries used, show all original rules.

2397

4. Check minimum number of events

None

2397

5. Include endpoints

None

2397

6. Filter based on genotype QC (FinnGen only)

2318

Control definitions (FinnGen only)

Control exclude K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K50
Name in latin Alis morbus Crohn specificatus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 14492 7232 7199
Only index persons 13958 7026 6932
Unadjusted period prevalence (%)
Whole population 0.20 0.21 0.20
Only index persons 0.26 0.26 0.26
Median age at first event (years)
Whole population 38.98 39.26 38.69
Only index persons 38.52 38.89 38.15

-FinnGen-

Key figures

All Female Male
Number of individuals 2318 1286 1032
Unadjusted period prevalence (%) 0.56 0.56 0.57
Median age at first event (years) 41.46 39.92 43.38

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: CHRONOTH – Other Crohn's disease

GWS hits: 13

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