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Ulcerative colitis (strict definition, require KELA)

DOID Endpoint Browser

K11_UC_STRICT

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

  • K11_KELAUC
6992

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K51
  • Hospital discharge: ICD-9 — 556
  • Hospital discharge: ICD-8 — 5631|569
  • Hospital discharge: excluded ICD-9 — 5564A
  • Cause of death: ICD-10 — K51
  • Cause of death: ICD-9 — 556
  • Cause of death: ICD-8 — 5631|569
  • Cause of death: excluded ICD-9 — 5564A

2 out of 7 registries used, show all original rules.

6385

4. Check minimum number of events

None

6385

5. Include endpoints

None

6385

6. Filter based on genotype QC (FinnGen only)

6203

Control definitions (FinnGen only)

Control exclude K11_UC_STRICT_PSC
Control conditions not K11_KELAUC

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3
Parent code in ICD-10 K50-K52
Name in latin Colitis ulcerosa

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 6203 3143 3060
Unadjusted period prevalence (%) 1.52 1.36 1.68
Median age at first event (years) 38.91 35.56 42.36

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: K11_UC_STRICT – Ulcerative colitis (strict definition, require KELA)

GWS hits: -

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