Asthma (only as main-diagnosis) (more control exclusions)

J10_ASTHMA_MAIN_EXMORE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Main diagnosis only: side diagnoses are not checked.

Registry filters:

  • Hospital discharge: ICD-10 J45, J46
  • Hospital discharge: ICD-9 493
  • Hospital discharge: ICD-8 493
  • Cause of death: ICD-10 J45, J46
  • Cause of death: ICD-9 493
  • Cause of death: ICD-8 493

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 459300 236544 220165
Only index persons 391893 207726 184167
Unadjusted period prevalence (%)
Whole population 6.45 6.78 6.15
Only index persons 7.35 7.64 7.03
Median age at first event (years)
Whole population 31.14 41.22 19.99
Only index persons 30.36 39.83 19.68

-FinnGen-

Key figures

All Female Male
Number of individuals 37759 23425 14334
Unadjusted period prevalence (%) 9.30 10.17 7.88
Median age at first event (years) 45.09 42.90 48.67

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: J10_ASTHMA_MAIN_EXMORE – Asthma (only as main-diagnosis) (more control exclusions)

GWS hits: 53

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