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Asthma (more control exclusions)

Endpoint Browser PheWeb

J10_ASTHMA_EXMORE

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

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2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — J45, J46
  • Hospital discharge: ICD-9 — 493
  • Hospital discharge: ICD-8 — 493
  • Cause of death: ICD-10 — J45, J46
  • Cause of death: ICD-9 — 493
  • Cause of death: ICD-8 — 493

2 out of 7 registries used, show all original rules.

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4. Check minimum number of events

None

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5. Include endpoints

None

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6. Filter based on genotype QC (FinnGen only)

None

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Control definitions (FinnGen only)

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

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Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 549294 287748 258223
Only index persons 469528 253690 215838
Unadjusted period prevalence (%)
Whole population 7.73 8.24 7.21
Only index persons 8.83 9.33 8.24
Median age at first event (years)
Whole population 37.27 45.52 27.78
Only index persons 35.48 44.12 25.32

-FinnGen-

Key figures

All Female Male
Number of individuals 46683 28570 18113
Unadjusted period prevalence (%) 11.46 12.41 9.96
Median age at first event (years) 48.22 45.40 52.66

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: J10_ASTHMA_EXMORE – Asthma (more control exclusions)

GWS hits: 61

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