Allergic asthma (mode)

ALLERG_ASTHMA

asthma: A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors resulting in recurring periods of wheezing (a whistling sound while breathing), chest tightness, shortness of breath, mucus production and coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Check mode of ICD-10 codes: %J450

Registry filters:

  • Hospital discharge: ICD-10 J45.0
  • Cause of death: ICD-10 J45.0

2 out of 7 registries used, show all original rules.

11139

4. Check minimum number of events

None

11139

5. Include endpoints

None

11139

6. Filter based on genotype QC (FinnGen only)

10723

Control definitions (FinnGen only)

Control exclude J10_ASTHMA, ASTHMA_EXCL

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 10723 7099 3624
Unadjusted period prevalence (%) 2.71 3.08 1.99
Median age at first event (years) 37.52 36.45 39.63

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ALLERG_ASTHMA – Allergic asthma (mode)

GWS hits: 28

loading spinner Loading Relationships table