heart valve disease: A disease involving the cardial valve.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
23606 |
6. Filter based on genotype QC (FinnGen only) |
22817 |
Control definitions (FinnGen only)
Control exclude
I9_OTHHEART
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Valvular heart disease excluding rheumatic fever
based on the number of shared cases.
Broader endpoints:
- Other heart diseases
- Other heart diseases
- Cardiovascular diseases (excluding rheumatic etc)
- Cardiovascular diseases
Narrower endpoints:
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 217192 | 107750 | 107449 |
| Only index persons | 176491 | 88289 | 88202 |
| Unadjusted period prevalence (%) | |||
| Whole population | 3.04 | 3.09 | 3.00 |
| Only index persons | 3.31 | 3.25 | 3.37 |
| Median age at first event (years) | |||
| Whole population | 71.71 | 74.29 | 69.13 |
| Only index persons | 71.19 | 73.61 | 68.76 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 22817 | 9606 | 13211 |
| Unadjusted period prevalence (%) | 5.96 | 4.17 | 7.27 |
| Median age at first event (years) | 68.81 | 68.95 | 68.71 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: I9_VHD – Valvular heart disease excluding rheumatic fever
GWS hits: 12
Loading Relationships table