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Calcific aortic valvular stenosis, diagnosis (helper)

I9_CAVS_DX

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — I35.0, I35.2
  • Hospital discharge: ICD-9 — 4241[BC]
  • Cause of death: ICD-10 — I35.0, I35.2
  • Cause of death: ICD-9 — 4241[BC]

2 out of 7 registries used, show all original rules.

10192

4. Check minimum number of events

None

10192

5. Include endpoints

None

10192

6. Filter based on genotype QC (FinnGen only)

9853

Control definitions (FinnGen only)

Control exclude I9_CAVS

Extra metadata

First used in FinnGen datafreeze DF6v3

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 9853 3644 6209
Unadjusted period prevalence (%) 2.74 1.58 3.42
Median age at first event (years) 72.67 74.07 71.85

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: I9_CAVS_DX – Calcific aortic valvular stenosis, diagnosis (helper)

GWS hits: -

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