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Calcific aortic valvular stenosis, including rheumatic fever

Endpoint Browser

I9_CAVS_RHEU

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — I06.0, I06.2, I35.0, I35.2
  • Hospital discharge: ICD-9 — 3950A|3952A|4241[BC]
  • Hospital discharge: ICD-8 — 39500|39502
  • Cause of death: ICD-10 — I06.0, I06.2, I35.0, I35.2
  • Cause of death: ICD-9 — 3950A|3952A|4241[BC]
  • Cause of death: ICD-8 — 39500|39502

2 out of 7 registries used, show all original rules.

10253

4. Check minimum number of events

None

10253

5. Include endpoints

None

10253

6. Filter based on genotype QC (FinnGen only)

9910

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF6v3

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 9910 3671 6239
Unadjusted period prevalence (%) 2.75 1.59 3.43
Median age at first event (years) 72.59 73.95 71.79

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: I9_CAVS_RHEU – Calcific aortic valvular stenosis, including rheumatic fever

GWS hits: -

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