No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditions
|
10209 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
10209 |
6. Filter based on genotype QC (FinnGen only) |
9870 |
Control definitions (FinnGen only)
Control conditions
not I9_CAVS_OPERATIONS1
or I9_CAVS_OPERATIONS2
or I9_CAVS_OPERATIONS2
Extra metadata
First used in FinnGen datafreeze
DF7
Similar endpoints
↥List of similar endpoints to
Calcific aortic valvular stenosis, operated
based on the number of shared cases.
Broader endpoints:
- Calcific aortic valvular stenosis
- Valvular heart disease excluding rheumatic fever
- Other heart diseases
- Other heart diseases
- Cardiovascular diseases (excluding rheumatic etc)
Narrower endpoints:
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 98668 | 48773 | 48987 |
| Only index persons | 79459 | 39185 | 40274 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.38 | 1.40 | 1.37 |
| Only index persons | 1.49 | 1.44 | 1.54 |
| Median age at first event (years) | |||
| Whole population | 75.89 | 78.69 | 73.13 |
| Only index persons | 75.73 | 78.58 | 72.96 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 9870 | 3653 | 6217 |
| Unadjusted period prevalence (%) | 2.74 | 1.59 | 3.42 |
| Median age at first event (years) | 72.65 | 74.04 | 71.83 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: I9_CAVS_OPERATED – Calcific aortic valvular stenosis, operated
GWS hits: 23
Loading Relationships table