Cardiovascular diseases (excluding rheumatic etc)

FG_CVD

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

208045

6. Filter based on genotype QC (FinnGen only)

201525

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2530258 1244524 1251506
Only index persons 1816911 950250 866661
Unadjusted period prevalence (%)
Whole population 35.31 35.65 34.97
Only index persons 34.05 34.93 33.08
Median age at first event (years)
Whole population 56.91 56.69 57.04
Only index persons 54.61 54.19 55.06

-FinnGen-

Key figures

All Female Male
Number of individuals 201525 96413 105112
Unadjusted period prevalence (%) 50.18 41.87 57.81
Median age at first event (years) 53.71 51.11 56.10

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: FG_CVD – Cardiovascular diseases (excluding rheumatic etc)

GWS hits: 87

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