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Pulmonary embolism

DOID EFO Endpoint Browser PheWeb

I9_PULMEMB

pulmonary embolism: The obstruction of the pulmonary artery or one of its branches by an embolus, sometimes associated with infarction of the lung.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — I26
  • Hospital discharge: ICD-9 — 415
  • Hospital discharge: ICD-8 — 450
  • Cause of death: ICD-10 — I26
  • Cause of death: ICD-9 — 415
  • Cause of death: ICD-8 — 450

2 out of 7 registries used, show all original rules.

10371

4. Check minimum number of events

None

10371

5. Include endpoints

None

10371

6. Filter based on genotype QC (FinnGen only)

10045

Control definitions (FinnGen only)

Control exclude I9_PULMHEART

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I26-I28
Name in latin Embolia pulmonalis

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 122590 66761 53967
Only index persons 82608 46099 36509
Unadjusted period prevalence (%)
Whole population 1.73 1.91 1.51
Only index persons 1.56 1.69 1.39
Median age at first event (years)
Whole population 70.01 71.92 67.63
Only index persons 68.28 70.19 65.87

-FinnGen-

Key figures

All Female Male
Number of individuals 10045 5047 4998
Unadjusted period prevalence (%) 2.47 2.19 2.75
Median age at first event (years) 65.40 64.05 66.77

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: I9_PULMEMB – Pulmonary embolism

GWS hits: 18

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