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Venous thromboembolism

DOID EFO Endpoint Browser PheWeb

I9_VTE

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — I26, I80, O87.1, O88.2
  • Hospital discharge: ICD-9 — 415|451|6713|6714|6732
  • Hospital discharge: ICD-8 — 450|451|671|6739
  • Hospital discharge: excluded ICD-10 — I80.0#
  • Hospital discharge: excluded ICD-9 — 4510
  • Cause of death: ICD-10 — I26, I80, O87.1, O88.2
  • Cause of death: ICD-9 — 415|451|6713|6714|6732
  • Cause of death: ICD-8 — 450|451|671|6739
  • Cause of death: excluded ICD-10 — I80.0#
  • Cause of death: excluded ICD-9 — 4510

2 out of 7 registries used, show all original rules.

21702

4. Check minimum number of events

None

21702

5. Include endpoints

None

21702

6. Filter based on genotype QC (FinnGen only)

21020

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 248674 138776 106624
Only index persons 178972 102819 76153
Unadjusted period prevalence (%)
Whole population 3.54 3.97 2.98
Only index persons 3.41 3.78 2.91
Median age at first event (years)
Whole population 65.14 66.44 63.36
Only index persons 62.36 63.33 61.06

-FinnGen-

Key figures

All Female Male
Number of individuals 21020 11157 9863
Unadjusted period prevalence (%) 5.12 4.85 5.42
Median age at first event (years) 60.12 57.62 62.94

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: I9_VTE – Venous thromboembolism

GWS hits: 50

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