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Hypertension, essential

DOID EFO Endpoint Browser PheWeb

I9_HYPTENSESS

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — I10
  • Hospital discharge: ICD-9 — 4039A|4019X
  • Hospital discharge: ICD-8 — 401|402|403|404
  • Cause of death: ICD-10 — I10
  • Cause of death: ICD-9 — 4039A|4019X
  • Cause of death: ICD-8 — 401|402|403|404

2 out of 7 registries used, show all original rules.

106137

4. Check minimum number of events

None

106137

5. Include endpoints

None

106137

6. Filter based on genotype QC (FinnGen only)

102862

Control definitions (FinnGen only)

Control exclude I9_HYPERTENSION

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I10-I15
Name in latin Hypertensio essentialis (primaria)

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1149373 614031 526783
Only index persons 972132 522927 449205
Unadjusted period prevalence (%)
Whole population 16.21 17.59 14.72
Only index persons 18.26 19.22 17.15
Median age at first event (years)
Whole population 67.73 70.23 64.85
Only index persons 67.52 69.91 64.74

-FinnGen-

Key figures

All Female Male
Number of individuals 102862 49558 53304
Unadjusted period prevalence (%) 25.56 21.52 29.32
Median age at first event (years) 64.38 63.93 64.81

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: I9_HYPTENSESS – Hypertension, essential

GWS hits: 224

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