Hypertension

I9_HYPTENS

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Suggest a new description

Endpoint definition

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Endpoint definition steps	FinnGen
Phenotype data	429209
1. Apply sex-specific rule None	429209
2. Check conditions None	429209
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — I10-I15, I67.4 Hospital discharge: ICD-9 — 4019X\|4029A\|4029B\|4039A\|4040A\|4059A\|4059B\|4372A\|4059X Hospital discharge: ICD-8 — 400\|401\|402\|403\|404 Cause of death: ICD-10 — I10-I15, I67.4 Cause of death: ICD-9 — 4019X\|4029A\|4029B\|4039A\|4040A\|4059A\|4059B\|4372A\|4059X Cause of death: ICD-8 — 400\|401\|402\|403\|404 KELA reimbursements: KELA codes — 205 3 out of 7 registries used, show all original rules.	126894
4. Check minimum number of events None	126894
5. Include endpoints None	126894
6. Filter based on genotype QC (FinnGen only)	122993

Control definitions (FinnGen only)

Control exclude I9_HYPERTENSION

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF2

NAME	I9_HYPTENS
CONTROL_EXCLUDE	I9_HYPERTENSION
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	I10\|I11\|I12\|I13\|I15\|I674
HD_ICD_9	4019X\|4029A\|4029B\|4039A\|4040A\|4059A\|4059B\|4372A\|4059X
HD_ICD_8	400\|401\|402\|403\|404
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	I10\|I11\|I12\|I13\|I15\|I674
COD_ICD_9	4019X\|4029A\|4029B\|4039A\|4040A\|4059A\|4059B\|4372A\|4059X
COD_ICD_8	400\|401\|402\|403\|404
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB	205
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

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List of similar endpoints to Hypertension based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Case counts by codes

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FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1425711	748182	664286
Only index persons	1146787	608887	537900
Unadjusted period prevalence (%)
Whole population	20.02	21.43	18.56
Only index persons	21.52	22.38	20.53
Median age at first event (years)
Whole population	59.25	60.87	57.47
Only index persons	59.13	60.74	57.31

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	122993	58214	64779
Unadjusted period prevalence (%)	30.73	25.28	35.63
Median age at first event (years)	56.92	56.66	57.15

≡ Risteys

FR+FG R10

FinnGen Risteys R10

FinnGen Risteys R9

FinnGen Risteys R8

FinnGen Risteys R7

FinnGen Risteys R6

FinnGen Risteys R5

FinnGen Risteys R4

FinnGen Risteys R3

Hypertension

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Hypertension (I9_HYPTENS)

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints