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Mental and behavioural disorders due to alcohol

F5_ALCOHOL

psychosis: An abnormal condition of the mind that involves a loss of contact with reality. People experiencing psychosis may exhibit personality changes and thought disorder. Depending on its severity, this may be accompanied by unusual or bizarre behavior, as well as difficulty with social interaction and impairment in carrying out daily life activities.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F10
  • Hospital discharge: ICD-9 303|291
  • Hospital discharge: ICD-8 291
  • Hospital discharge: excluded ICD-10 F10.0
  • Cause of death: ICD-10 F10
  • Cause of death: ICD-9 303|291
  • Cause of death: ICD-8 291
  • Cause of death: excluded ICD-10 F10.1

2 out of 7 registries used, show all original rules.

18495

4. Check minimum number of events

None

18495

5. Include endpoints

22851

6. Filter based on genotype QC (FinnGen only)

22189

Control definitions (FinnGen only)

Control exclude F5_SUBSTANCE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5
Parent code in ICD-10 F10-F19
Name in latin Perturbationes mentis et modi se gerendi ex usu alcohol

Similar endpoints

List of similar endpoints to Mental and behavioural disorders due to alcohol based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 22189 7224 14965
Unadjusted period prevalence (%) 6.57 3.14 8.23
Median age at first event (years) 45.37 40.35 47.80

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: F5_ALCOHOL – Mental and behavioural disorders due to alcohol

GWS hits: -

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