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Alcohol dependence

DOID EFO Endpoint Browser PheWeb

F5_ALCOHOL_DEPENDENCE

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F10.2
  • Hospital discharge: ICD-9 — 303
  • Hospital discharge: ICD-8 — 303
  • Cause of death: ICD-10 — F10.2
  • Cause of death: ICD-9 — 303
  • Cause of death: ICD-8 — 303

2 out of 7 registries used, show all original rules.

11012

4. Check minimum number of events

None

11012

5. Include endpoints

None

11012

6. Filter based on genotype QC (FinnGen only)

10707

Control definitions (FinnGen only)

Control exclude F5_SUBSTANCE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3
Parent code in ICD-10 F10

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 173620 38412 132315
Only index persons 117725 30256 87469
Unadjusted period prevalence (%)
Whole population 3.11 1.10 3.70
Only index persons 2.77 1.11 3.34
Median age at first event (years)
Whole population 43.59 43.96 43.40
Only index persons 42.89 43.51 42.67

-FinnGen-

Key figures

All Female Male
Number of individuals 10707 2919 7788
Unadjusted period prevalence (%) 3.46 1.27 4.28
Median age at first event (years) 42.91 40.95 43.65

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: F5_ALCOHOL_DEPENDENCE – Alcohol dependence

GWS hits: 6

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