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Alcohol use disorder, ICD-based

EFO Endpoint Browser PheWeb

AUD

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F10.1, F10.2
  • Hospital discharge: ICD-9 — 303
  • Hospital discharge: ICD-8 — 303
  • Cause of death: ICD-10 — F10.1, F10.2
  • Cause of death: ICD-9 — 303
  • Cause of death: ICD-8 — 303

2 out of 7 registries used, show all original rules.

17702

4. Check minimum number of events

None

17702

5. Include endpoints

None

17702

6. Filter based on genotype QC (FinnGen only)

17197

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF5

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 263725 67743 192653
Only index persons 199840 58053 141787
Unadjusted period prevalence (%)
Whole population 4.47 1.94 5.38
Only index persons 4.46 2.13 5.41
Median age at first event (years)
Whole population 44.24 43.33 44.49
Only index persons 43.51 42.51 43.92

-FinnGen-

Key figures

All Female Male
Number of individuals 17197 5463 11734
Unadjusted period prevalence (%) 5.16 2.37 6.45
Median age at first event (years) 44.73 40.87 46.53

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: AUD – Alcohol use disorder, ICD-based

GWS hits: 10

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