Asthma-related pneumonia

ASTHMA_PNEUMONIA

pneumonia: An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, caused by an infection in one or both of the lungs (by bacteria, viruses, fungi, or mycoplasma.). Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

  • J10_ASTHMA
48366

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

13664

6. Filter based on genotype QC (FinnGen only)

13185

Control definitions (FinnGen only)

Control exclude ASTHMA_INFECTIONS
Control conditions not J10_ASTHMA

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 149546 76459 71699
Only index persons 120997 64203 56794
Unadjusted period prevalence (%)
Whole population 2.09 2.19 2.00
Only index persons 2.27 2.36 2.17
Median age at first event (years)
Whole population 62.91 65.53 59.96
Only index persons 59.79 63.39 55.73

-FinnGen-

Key figures

All Female Male
Number of individuals 13185 6761 6424
Unadjusted period prevalence (%) 3.23 2.94 3.53
Median age at first event (years) 60.62 56.01 65.47

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: ASTHMA_PNEUMONIA – Asthma-related pneumonia

GWS hits: 11

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