Asthma mixed form (mode) (more control exclusions)

ASTHMA_MIXED_EXMORE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Check mode of ICD-10 codes: %J458

Registry filters:

  • Hospital discharge: ICD-10 J45.8
  • Cause of death: ICD-10 J45.8

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 25457 12665 12623
Only index persons 21583 11039 10544
Unadjusted period prevalence (%)
Whole population 0.36 0.36 0.35
Only index persons 0.40 0.41 0.40
Median age at first event (years)
Whole population 40.31 48.39 31.78
Only index persons 36.53 46.30 26.30

-FinnGen-

Key figures

All Female Male
Number of individuals 1959 1129 830
Unadjusted period prevalence (%) 0.48 0.49 0.46
Median age at first event (years) 53.43 47.94 60.89

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: ASTHMA_MIXED_EXMORE – Asthma mixed form (mode) (more control exclusions)

GWS hits: -

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