Childhood asthma (age<16) (more control exclusions)

ASTHMA_CHILD_EXMORE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Pre-conditions: EVENT_AGE<16

Registry filters:

  • Hospital discharge: ICD-10 J45, J46
  • Hospital discharge: ICD-9 493
  • Hospital discharge: ICD-8 493
  • Cause of death: ICD-10 J45, J46
  • Cause of death: ICD-9 493
  • Cause of death: ICD-8 493

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

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Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 173424 66892 106463
Only index persons 146118 57018 89100
Unadjusted period prevalence (%)
Whole population 2.57 1.92 2.97
Only index persons 2.89 2.10 3.40
Median age at first event (years)
Whole population 4.94 5.63 4.51
Only index persons 5.54 6.34 5.02

-FinnGen-

Key figures

All Female Male
Number of individuals 6603 3876 2727
Unadjusted period prevalence (%) 1.61 1.68 1.50
Median age at first event (years) 7.11 7.87 6.02

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: ASTHMA_CHILD_EXMORE – Childhood asthma (age<16) (more control exclusions)

GWS hits: 24

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