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Wet age-related macular degeneration

WET_AMD_EARLY

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Pre-conditions: EVENT_AGE<50

Registry filters:

  • Hospital discharge: ICD-10 H35.31
  • Hospital discharge: ICD-9 3625B
  • Cause of death: ICD-10 H35.31
  • Cause of death: ICD-9 3625B

2 out of 7 registries used, show all original rules.

88

4. Check minimum number of events

None

88

5. Include endpoints

None

88

6. Filter based on genotype QC (FinnGen only)

81

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3
Parent code in ICD-10 H35
Name in latin Degeneratio maculae senilis exsudativa

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 81 45 36
Unadjusted period prevalence (%) 0.02 0.02 0.02
Median age at first event (years) 41.69 40.36 43.35

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: WET_AMD_EARLY – Wet age-related macular degeneration

GWS hits: -

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