pulmonary tuberculosis: A bacterial infection that affects the lungs and is caused by Mycobacterium tuberculosis. Most patients with tuberculosis do not have symptoms (latent tuberculosis) and are not contagious. When signs and symptoms occur (active tuberculosis), patients become contagious. The signs and symptoms include chronic cough with blood-tinged sputum, night sweats, fever, fatigue, and weight loss.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
2012 |
6. Filter based on genotype QC (FinnGen only) |
1929 |
Control definitions (FinnGen only)
Control exclude
IBD_TUBERCULOSIS
Extra metadata
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Respiratory tuberculosis
based on the number of shared cases.
Broader endpoints:
- Respiratory tuberculosis
- Tuberculosis
- Tuberculosis, IBD comorbidity
- Tuberculosis
- Infections, IBD-co-morbidities
Narrower endpoints:
- Respiratory tuberculosis
- Respiratory tuberculosis, not confirmed bacteriologically or histologically
- Respiratory TBC, ICD-8 codes not specifying whether confirmed bacteriologically or histologically
- Respiratory tuberculosis, bacteriologically and histologically confirmed
- Respiratory tuberculosis, bacteriologically and histologically confirmed
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 34910 | 13713 | 20113 |
| Only index persons | 17505 | 8163 | 9342 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.51 | 0.39 | 0.56 |
| Only index persons | 0.33 | 0.30 | 0.36 |
| Median age at first event (years) | |||
| Whole population | 53.02 | 52.55 | 53.15 |
| Only index persons | 42.73 | 41.60 | 43.72 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1929 | 640 | 1289 |
| Unadjusted period prevalence (%) | 0.57 | 0.28 | 0.71 |
| Median age at first event (years) | 46.25 | 36.88 | 50.90 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: TBC_RESP – Respiratory tuberculosis
GWS hits: -
Loading Relationships table