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Parkinson's disease, strict definition (more control exclusions)

PDSTRICT_EXMORE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G20
  • Hospital discharge: ICD-9 3320A
  • Hospital discharge: ICD-8 34200
  • Cause of death: ICD-10 G20
  • Cause of death: ICD-9 3320A
  • Cause of death: ICD-8 34200
  • KELA reimbursements: KELA codes 110
  • KELA reimbursements: ICD-10 G20, G20+F02.39

3 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude G6_PARKINSON, F5_PSYCH, NEURODIS

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 G20-G26
Name in latin Morbus Parkinson

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population - - -
Only index persons - - -
Unadjusted period prevalence (%)
Whole population - - -
Only index persons - - -
Median age at first event (years)
Whole population - - -
Only index persons - - -

-FinnGen-

Key figures

All Female Male
Number of individuals 4231 1651 2580
Unadjusted period prevalence (%) 1.15 0.72 1.42
Median age at first event (years) 70.09 69.19 70.66

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: PDSTRICT_EXMORE – Parkinson's disease, strict definition (more control exclusions)

GWS hits: -

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