info icon

Parkinson's disease, strict definition


secondary Parkinson disease: Conditions which feature clinical manifestations resembling primary Parkinson disease that are caused by a known or suspected condition. Examples include parkinsonism caused by vascular injury, drugs, trauma, toxin exposure, neoplasms, infections and degenerative or hereditary conditions. Clinical features may include bradykinesia, rigidity, parkinsonian gait, and masked facies. In general, tremor is less prominent in secondary parkinsonism than in the primary form. (From Joynt, Clinical Neurology, 1998, Ch38, pp39-42)

Suggest a new description

Endpoint definition

Endpoint definition steps


Phenotype data


1. Apply sex-specific rule



2. Check conditions



3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G20
  • Hospital discharge: ICD-9 3320A
  • Hospital discharge: ICD-8 34200
  • Cause of death: ICD-10 G20
  • Cause of death: ICD-9 3320A
  • Cause of death: ICD-8 34200
  • KELA reimbursements: KELA codes 110
  • KELA reimbursements: ICD-10 G20, G20+F02.39

3 out of 7 registries used, show all original rules.


4. Check minimum number of events



5. Include endpoints



6. Filter based on genotype QC (FinnGen only)


Control definitions (FinnGen only)

Control exclude G6_PARKINSON

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 G20-G26
Name in latin Morbus Parkinson

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics


This endpoint is excluded from FinRegistry analyses (omitted endpoint).


Key figures

All Female Male
Number of individuals 4231 1651 2580
Unadjusted period prevalence (%) 1.15 0.72 1.42
Median age at first event (years) 70.09 69.19 70.66


Age distribution of first events


Year distribution of first events


Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: PDSTRICT – Parkinson's disease, strict definition

GWS hits: -

loading spinner Loading Relationships table