No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1645 |
4. Check minimum number of eventsNone |
1645 |
5. Include endpoints |
2067 |
6. Filter based on genotype QC (FinnGen only) |
2005 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF7
Similar endpoints
↥List of similar endpoints to
Mixed connective tissue disease
based on the number of shared cases.
Broader endpoints:
- Other systemic involvement of connective tissue (FG)
- Other systemic involvement of connective tissue
- Systemic connective tissue disorders
- Finngen Rheumatological endpoints
- Autoimmune diseases
Narrower endpoints:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 14204 | 11040 | 3044 |
| Only index persons | 12490 | 9991 | 2499 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.27 | 0.32 | 0.09 |
| Only index persons | 0.31 | 0.37 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 54.56 | 53.37 | 58.70 |
| Only index persons | 52.81 | 51.86 | 56.64 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2005 | 1605 | 400 |
| Unadjusted period prevalence (%) | 0.60 | 0.70 | 0.22 |
| Median age at first event (years) | 51.73 | 50.00 | 58.70 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: M13_MCTD – Mixed connective tissue disease
GWS hits: 3
Loading Relationships table