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Gout

DOID EFO Endpoint Browser PheWeb

M13_GOUT

gout: A condition characterized by painful swelling of the joints, which is caused by deposition of urate crystals.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M10
  • Hospital discharge: ICD-9 — 2740
  • Hospital discharge: ICD-8 — 2740
  • Cause of death: ICD-10 — M10
  • Cause of death: ICD-9 — 2740
  • Cause of death: ICD-8 — 2740
  • KELA reimbursements: KELA codes — 212

3 out of 7 registries used, show all original rules.

9892

4. Check minimum number of events

None

9892

5. Include endpoints

None

9892

6. Filter based on genotype QC (FinnGen only)

9568

Control definitions (FinnGen only)

Control exclude M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M05-M14

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 106476 34310 70743
Only index persons 80076 25035 55041
Unadjusted period prevalence (%)
Whole population 1.65 0.98 1.98
Only index persons 1.73 0.92 2.10
Median age at first event (years)
Whole population 69.14 75.51 66.10
Only index persons 68.92 75.83 65.77

-FinnGen-

Key figures

All Female Male
Number of individuals 9568 2241 7327
Unadjusted period prevalence (%) 3.31 0.97 4.03
Median age at first event (years) 66.58 69.21 65.78

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: M13_GOUT – Gout

GWS hits: 16

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