Gout, strict definition

GOUT_STRICT

gout: A condition characterized by painful swelling of the joints, which is caused by deposition of urate crystals.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

  • GOUT_IDIOP_NOS
7622

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC M04AA01|M04AA03|M04AB01|M04AB03

1 out of 7 registries used, show all original rules.

5336

4. Check minimum number of events

Min. number of events 3
5336

5. Include endpoints

None

5336

6. Filter based on genotype QC (FinnGen only)

5162

Control definitions (FinnGen only)

Control conditions not GOUT_IDIOP_NOS

Extra metadata

First used in FinnGen datafreeze DF3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 49278 14513 34493
Only index persons 44249 12661 31588
Unadjusted period prevalence (%)
Whole population 0.80 0.42 0.96
Only index persons 0.99 0.47 1.21
Median age at first event (years)
Whole population 66.54 74.20 63.27
Only index persons 65.57 73.23 62.49

-FinnGen-

Key figures

All Female Male
Number of individuals 5162 1054 4108
Unadjusted period prevalence (%) 1.89 0.46 2.26
Median age at first event (years) 62.81 66.59 61.84

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: GOUT_STRICT – Gout, strict definition

GWS hits: 10

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