Behcet's syndrome: Bechet disease (BD) is a chronic, relapsing, multisystemic vasculitis characterized by mucocutaneous lesions, as well as articular, vascular, ocular and central nervous system manifestations.
Endpoint definition
↥
						Endpoint definition steps | 
					
						FinnGen | 
				
|---|---|
						Phenotype data | 
					429209 | 
								1. Apply sex-specific ruleNone  | 
							429209 | 
								2. Check conditionsNone  | 
							429209 | 
								3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 
 2 out of 7 registries used, show all original rules.  | 
							
								 94  | 
						
								4. Check minimum number of eventsNone  | 
							94 | 
								5. Include endpointsNone  | 
							94 | 
										6. Filter based on genotype QC (FinnGen only) | 
									90 | 
Control definitions (FinnGen only)
					Control exclude
					M13_SYSTCONNECT
				
			Extra metadata
					Level in the ICD hierarchy
					4
				
				
					First used in FinnGen datafreeze
					DF2
				
				
					Parent code in ICD-10
					M35
				
				
					Name in latin
					Morbus Behçet
				
			Similar endpoints
↥List of similar endpoints to
		
Behçet disease
	based on the number of shared cases.
		
		Broader endpoints:
	
- Other systemic involvement of connective tissue (FG)
 - Other systemic involvement of connective tissue
 - Systemic connective tissue disorders
 - Finngen Rheumatological endpoints
 - Autoimmune diseases
 
		
		Narrower endpoints:
	
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 612 | 415 | 187 | 
| Only index persons | 535 | 378 | 157 | 
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 | 
| Only index persons | 0.01 | 0.01 | 0.01 | 
| Median age at first event (years) | |||
| Whole population | 53.29 | 53.02 | 54.96 | 
| Only index persons | 51.23 | 50.44 | 53.11 | 
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 90 | 68 | 22 | 
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.01 | 
| Median age at first event (years) | 49.01 | 46.69 | 56.20 | 
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: M13_BEHCET – Behçet disease
GWS hits: -
                
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