psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
10267 |
4. Check minimum number of eventsNone |
10267 |
5. Include endpoints |
10713 |
6. Filter based on genotype QC (FinnGen only) |
10312 |
Control definitions (FinnGen only)
Control exclude
L12_PAPULOSQUAMOUS
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L40-L45
Name in latin
Psoriasis
Similar endpoints
↥List of similar endpoints to
Psoriasis
based on the number of shared cases.
Broader endpoints:
- Papulosquamous disorders
- Autoimmune diseases related-to ILD
- Autoimmune diseases
- Diseases of the skin and subcutaneous tissue
- Used for control exclusion in common control thyroid runs
Narrower endpoints:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 86247 | 41718 | 43977 |
| Only index persons | 78371 | 38990 | 39381 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.21 | 1.19 | 1.23 |
| Only index persons | 1.47 | 1.43 | 1.50 |
| Median age at first event (years) | |||
| Whole population | 50.13 | 51.32 | 48.96 |
| Only index persons | 49.42 | 50.73 | 48.14 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 10312 | 5400 | 4912 |
| Unadjusted period prevalence (%) | 2.51 | 2.35 | 2.70 |
| Median age at first event (years) | 51.24 | 50.58 | 51.97 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: L12_PSORIASIS – Psoriasis
GWS hits: 41
Loading Relationships table