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Other and unspecified psoriasis

DOID EFO Endpoint Browser PheWeb

L12_PSORI_NAS

psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — L40.8, L40.9
  • Hospital discharge: ICD-9 — 6968X
  • Hospital discharge: ICD-8 — 69619
  • Cause of death: ICD-10 — L40.8, L40.9
  • Cause of death: ICD-9 — 6968X
  • Cause of death: ICD-8 — 69619

2 out of 7 registries used, show all original rules.

1968

4. Check minimum number of events

None

1968

5. Include endpoints

None

1968

6. Filter based on genotype QC (FinnGen only)

1910

Control definitions (FinnGen only)

Control exclude L12_PAPULOSQUAMOUS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17507 7898 9423
Only index persons 14685 6954 7731
Unadjusted period prevalence (%)
Whole population 0.25 0.23 0.26
Only index persons 0.28 0.26 0.30
Median age at first event (years)
Whole population 50.61 51.59 49.78
Only index persons 49.46 50.13 48.86

-FinnGen-

Key figures

All Female Male
Number of individuals 1910 938 972
Unadjusted period prevalence (%) 0.47 0.41 0.53
Median age at first event (years) 50.00 48.75 51.20

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: L12_PSORI_NAS – Other and unspecified psoriasis

GWS hits: 4

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