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Generalized pustular psoriasis

DOID EFO Endpoint Browser PheWeb

L12_PSORI_PUSTGEN

impetigo herpetiformis: An impetigo that is characterized as a form of severe pustular psoriasis occurring in pregnancy.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — L40.1
  • Hospital discharge: ICD-9 — 6961B
  • Hospital discharge: ICD-8 — 69610
  • Cause of death: ICD-10 — L40.1
  • Cause of death: ICD-9 — 6961B
  • Cause of death: ICD-8 — 69610

2 out of 7 registries used, show all original rules.

105

4. Check minimum number of events

None

105

5. Include endpoints

None

105

6. Filter based on genotype QC (FinnGen only)

101

Control definitions (FinnGen only)

Control exclude L12_PAPULOSQUAMOUS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L40
Name in latin Psoriasis pustulosa generalisata

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 983 481 487
Only index persons 740 384 356
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 54.30 56.74 51.88
Only index persons 52.55 54.23 50.72

-FinnGen-

Key figures

All Female Male
Number of individuals 101 52 49
Unadjusted period prevalence (%) 0.02 0.02 0.03
Median age at first event (years) 53.04 51.66 54.52

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: L12_PSORI_PUSTGEN – Generalized pustular psoriasis

GWS hits: -

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