Heart failure and hypertrophic cardiomyopathy

I9_HEARTFAIL_AND_HYPERTCARDIOM

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

  • I9_HYPERTROCARDMYOP
1172

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

473

6. Filter based on genotype QC (FinnGen only)

454

Control definitions (FinnGen only)

Control conditions not I9_HYPERTROCARDMYOP

Extra metadata

First used in FinnGen datafreeze DF5

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3880 1606 2239
Only index persons 3162 1299 1863
Unadjusted period prevalence (%)
Whole population 0.06 0.05 0.06
Only index persons 0.06 0.05 0.07
Median age at first event (years)
Whole population 64.57 67.92 62.15
Only index persons 64.98 68.74 62.35

-FinnGen-

Key figures

All Female Male
Number of individuals 454 159 295
Unadjusted period prevalence (%) 0.13 0.07 0.16
Median age at first event (years) 61.19 63.20 60.10

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: I9_HEARTFAIL_AND_HYPERTCARDIOM – Heart failure and hypertrophic cardiomyopathy

GWS hits: 5

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