hypertrophic cardiomyopathy: A condition in which the myocardium is hypertrophied without an obvious cause. The hypertrophy is generally asymmetric and may be associated with obstruction of the ventricular outflow tract.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1172 |
4. Check minimum number of eventsNone |
1172 |
5. Include endpointsNone |
1172 |
6. Filter based on genotype QC (FinnGen only) |
1125 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF3
Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 9589 | 3813 | 5697 |
Only index persons | 8026 | 3216 | 4810 |
Unadjusted period prevalence (%) | |||
Whole population | 0.14 | 0.11 | 0.16 |
Only index persons | 0.16 | 0.12 | 0.18 |
Median age at first event (years) | |||
Whole population | 62.13 | 65.75 | 59.66 |
Only index persons | 61.60 | 64.96 | 59.35 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 1125 | 455 | 670 |
Unadjusted period prevalence (%) | 0.30 | 0.20 | 0.37 |
Median age at first event (years) | 60.24 | 58.63 | 61.33 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: I9_HYPERTROCARDMYOP – Hypertrophic cardiomyopathy
GWS hits: 21
Loading Relationships table