Heart failure and coronary heart disease

I9_HEARTFAIL_AND_CHD

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

  • I9_CHD
48549

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

14455

6. Filter based on genotype QC (FinnGen only)

13952

Control definitions (FinnGen only)

Control conditions not I9_CHD

Extra metadata

First used in FinnGen datafreeze DF5

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 230776 111300 115379
Only index persons 135233 65163 70070
Unadjusted period prevalence (%)
Whole population 3.22 3.19 3.22
Only index persons 2.54 2.40 2.67
Median age at first event (years)
Whole population 73.67 75.63 71.88
Only index persons 75.15 77.47 72.98

-FinnGen-

Key figures

All Female Male
Number of individuals 13952 4020 9932
Unadjusted period prevalence (%) 4.39 1.75 5.46
Median age at first event (years) 71.73 72.59 71.38

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: I9_HEARTFAIL_AND_CHD – Heart failure and coronary heart disease

GWS hits: 19

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