Major coronary heart disease event

I9_CHD

intermediate coronary syndrome: Precordial pain at rest, which may precede a MYOCARDIAL INFARCTION.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Main diagnosis only: side diagnoses are not checked.

Registry filters:

  • Hospital discharge: ICD-10 I20.0, I21, I22
  • Hospital discharge: ICD-9 410|4110
  • Hospital discharge: ICD-8 410|4110
  • Cause of death: ICD-10 I21, I22, I23, I24, I25, I46, R96, R98
  • Cause of death: ICD-9 41[0-4]|798
  • Cause of death: ICD-8 41[0-4]|798
  • Cause of death: excluded ICD-9 7980A

2 out of 7 registries used, show all original rules.

38431

4. Check minimum number of events

None

38431

5. Include endpoints

48549

6. Filter based on genotype QC (FinnGen only)

46959

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 732921 276052 440492
Only index persons 390286 156444 233842
Unadjusted period prevalence (%)
Whole population 10.76 7.91 12.31
Only index persons 7.65 5.75 8.93
Median age at first event (years)
Whole population 69.86 75.87 66.19
Only index persons 69.43 75.36 65.46

-FinnGen-

Key figures

All Female Male
Number of individuals 46959 13433 33526
Unadjusted period prevalence (%) 14.83 5.83 18.44
Median age at first event (years) 66.55 68.78 65.65

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: I9_CHD – Major coronary heart disease event

GWS hits: 90

loading spinner Loading Relationships table