Coronary angioplasty

I9_ANGIO

Coronary Vasospasm: Sudden coronary artery smooth muscle contraction leading to lumen constriction and decreased blood flow.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Operations: NOMESCO codes ^FNF|^FNG|^TFN40|^FN1AT|^FN1BT|^FN1YT
  • Operations: Heart Patient codes v1 ^82$|^83$|^84$
  • Operations: Heart Patient codes v2 ^AN2|^AN3|^AN4|^ANA|^ANB

1 out of 7 registries used, show all original rules.

16280

4. Check minimum number of events

None

16280

5. Include endpoints

None

16280

6. Filter based on genotype QC (FinnGen only)

15779

Control definitions (FinnGen only)

Control exclude I9_ISCHHEART

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 125240 40017 84719
Only index persons 116189 37179 79010
Unadjusted period prevalence (%)
Whole population 1.97 1.15 2.37
Only index persons 2.49 1.37 3.02
Median age at first event (years)
Whole population 66.86 71.40 64.69
Only index persons 66.69 71.31 64.51

-FinnGen-

Key figures

All Female Male
Number of individuals 15779 4416 11363
Unadjusted period prevalence (%) 5.04 1.92 6.25
Median age at first event (years) 65.53 67.06 64.94

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: I9_ANGIO – Coronary angioplasty

GWS hits: 53

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