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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Cerebral atherosclerosis

I9_CERATHER

cerebral atherosclerosis: Vascular diseases characterized by thickening and hardening of the walls of ARTERIES inside the SKULL. There are three subtypes: (1) atherosclerosis with fatty deposits in the ARTERIAL INTIMA; (2) Monckeberg's sclerosis with calcium deposits in the media and (3) arteriolosclerosis involving the small caliber arteries. Clinical signs include HEADACHE; CONFUSION; transient blindness (AMAUROSIS FUGAX); speech impairment; and HEMIPARESIS.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 I67.2
  • Hospital discharge: ICD-9 4370
  • Hospital discharge: ICD-8 437
  • Cause of death: ICD-10 I67.2
  • Cause of death: ICD-9 4370
  • Cause of death: ICD-8 437

2 out of 7 registries used, show all original rules.

354

4. Check minimum number of events

None

354

5. Include endpoints

None

354

6. Filter based on genotype QC (FinnGen only)

342

Control definitions (FinnGen only)

Control exclude I9_CEREBVASC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I67
Name in latin Atherosclerosis cerebralis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 342 117 225
Unadjusted period prevalence (%) 0.10 0.05 0.12
Median age at first event (years) 72.72 71.81 73.19

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: I9_CERATHER – Cerebral atherosclerosis

GWS hits: -

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