Other disorders of cornea

H7_CORNEALOTH

corneal disease: A non-neoplastic or neoplastic disorder that affects the cornea. Representative examples include keratitis, bullous keratopathy, and squamous cell carcinoma.

Suggest a new description

Endpoint definition

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Endpoint definition steps	FinnGen
Phenotype data	429209
1. Apply sex-specific rule None	429209
2. Check conditions None	429209
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — H18 Cause of death: ICD-10 — H18 2 out of 7 registries used, show all original rules.	2785
4. Check minimum number of events None	2785
5. Include endpoints H7_CORNEAPIGMENT H7_BULLKERATOPATHY H7_CORNEALOEDEMA H7_CORNEALMEMBRANE H7_CORNEALDYSTROPHY H7_KERATOCONUS H7_CORNEALDEFORM H7_CORNEALNAS	2881
6. Filter based on genotype QC (FinnGen only)	2776

Control definitions (FinnGen only)

Control exclude H7_SCLERACORNEA

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H15-H22

Name in latin Aliae morbositates corneae

NAME	H7_CORNEALOTH
CONTROL_EXCLUDE	H7_SCLERACORNEA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	H7_CORNEAPIGMENT\|H7_BULLKERATOPATHY\|H7_CORNEALOEDEMA\|H7_CORNEALMEMBRANE\|H7_CORNEALDYSTROPHY\|H7_KERATOCONUS\|H7_CORNEALDEFORM\|H7_CORNEALNAS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H18
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H18
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

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List of similar endpoints to Other disorders of cornea based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Case counts by codes

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FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	27514	14348	13021
Only index persons	25515	13289	12226
Unadjusted period prevalence (%)
Whole population	0.39	0.41	0.36
Only index persons	0.48	0.49	0.47
Median age at first event (years)
Whole population	52.38	59.94	44.18
Only index persons	51.37	58.67	43.44

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	2776	1588	1188
Unadjusted period prevalence (%)	0.67	0.69	0.65
Median age at first event (years)	54.43	55.99	52.34

≡ Risteys

FR+FG R10

FinnGen Risteys R10

FinnGen Risteys R9

FinnGen Risteys R8

FinnGen Risteys R7

FinnGen Risteys R6

FinnGen Risteys R5

FinnGen Risteys R4

FinnGen Risteys R3

Other disorders of cornea

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Other disorders of cornea (H7_CORNEALOTH)

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints