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Diabetic neuropathy

DOID Endpoint Browser

G6_DIABETNEUR

diabetic neuropathy: A chronic, pathological complication associated with diabetes mellitus, where nerve damages are incurred due to diabetic microvascular injury involving small blood vessels that supply these nerves, resulting in peripheral and/or autonomic nerve dysfunction.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — G590|E104|E114|E124|E134|E144
  • Hospital discharge: ICD-9 — 2505
  • Hospital discharge: ICD-8 — 25005
  • Cause of death: ICD-10 — G590|E104|E114|E124|E134|E144
  • Cause of death: ICD-9 — 2505
  • Cause of death: ICD-8 — 25005

2 out of 7 registries used, show all original rules.

3173

4. Check minimum number of events

None

3173

5. Include endpoints

None

3173

6. Filter based on genotype QC (FinnGen only)

3064

Control definitions (FinnGen only)

Control exclude G6_NERPLEX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 3064 1087 1977
Unadjusted period prevalence (%) 0.87 0.47 1.09
Median age at first event (years) 58.38 55.34 60.05

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: G6_DIABETNEUR – Diabetic neuropathy

GWS hits: -

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